Elisabeth Bloemena - bibliography

  • Schouten CS, Hakim S, Boellaard R, Bloemena E, Doornaert PA, Witte BI, Braakhuis BJ,
    Brakenhoff RH, Leemans CR, Hoekstra OS, de Bree R.
    Interaction of quantitative 18F-FDG-PET-CT imaging parameters and human papillomavirus status in oropharyngeal squamous cell carcinoma.
    Head Neck. 2014 Oct 29. [Epub ahead of print]
  • Eskens FA, van Erpecum KJ, de Jong KP, van Delden OM, Klumpen HJ, Verhoef C, Jansen PL,
    van den Bosch MA, Méndez Romero A, Verheij J, Bloemena E, de Man RA.
    Hepatocellular carcinoma: Dutch guideline for surveillance, diagnosis and therapy.
    Neth J Med. 2014 Jul;72(6):299-304.
  • de Boer YS, van Nieuwkerk CM, Witte BI, Mulder CJ, Bouma G, Bloemena E.
    The assessment of the histopathological key-features in autoimmune hepatitis.
    Histopathology. 2014 Sep 26. [Epub ahead of print]
  • Flach GB, Bloemena E, Klop WM, van Es RJ, Schepman KP, Hoekstra OS, Castelijns JA,
    Leemans CR, de Bree R.
    Sentinel lymph node biopsy in clinically N0 T1-T2 staged oral cancer: the Dutch multicenter trial.
    Oral Oncol. 2014 Oct;50(10):1020-4. Epub 2014 Aug 19.
  • van Stein-Callenfels D, Tan J, Bloemena E, van Vugt RM, Voskuyl AE, Santana NT,
    van der Waal I.
    The role of a labial salivary gland biopsy in the diagnostic procedure for Sjögren's syndrome;
    a study of 94 cases.
    Med Oral Patol Oral Cir Bucal. 2014 Jul 1;19(4):e372-6.
  • de Boer YS, van Gerven NM, Zwiers A, Verwer BJ, van Hoek B, van Erpecum KJ, Beuers U,
    van Buuren HR, Drenth JP, den Ouden JW, Verdonk RC, Koek GH, Brouwer JT, Guichelaar MM, Vrolijk JM, Kraal G, Mulder CJ, van Nieuwkerk CM, Fischer J, Berg T, Stickel F, Sarrazin C, Schramm C, Lohse AW, Weiler-Normann C, Lerch MM, Nauck M, Völzke H, Homuth G,
    Bloemena E, Verspaget HW, Kumar V, Zhernakova A, Wijmenga C, Franke L, Bouma G.
    Genome-wide association study identifies variants associated with autoimmune hepatitis
    type 1.
    Gastroenterology. 2014 Aug;147(2):443-52.e5. Epub 2014 Apr 23.
  • Den Toom IJ, Heuveling DA, Flach GB, Van Weert S, Karagozoglu KH, Van Schie A,
    Bloemena E
    , Leemans CR, De Bree R.
    Sentinel node biopsy for early stage oral cavity cancer: The VU University Medical Center experience.
    Head Neck. 2014 Feb 20.
  • Rietbergen MM, Martens-de Kemp SR, Bloemena E, Witte BI, Brink A, Baatenburg de Jong RJ, Leemans CR, Braakhuis BJ, Brakenhoff RH.
    Cancer stem cell enrichment marker CD98: a prognostic factor for survival in patients with human papillomavirus-positive oropharyngeal cancer.
    Eur J Cancer. 2014 Mar;50(4):765-73.
  • Rietbergen MM, Snijders PJ, Beekzada D, Braakhuis BJ, Brink A, Heideman DA, Hesselink AT, Witte BI, Bloemena E, Baatenburg-De Jong RJ, Leemans CR, Brakenhoff RH.
    Molecular characterization of p16-immunopositive but HPV DNA-negative oropharyngeal carcinomas. Int J Cancer. 2014 May 15;134(10):2366-72.
  • Graveland AP, Bremmer JF, de Maaker M, Brink A, Cobussen P, Zwart M, Braakhuis BJ, Bloemena E, van der Waal I, Leemans CR, Brakenhoff RH.

    Molecular screening of oral precancer.

    Oral Oncol. 2013 Dec;49(12):1129-35.
  • van der Putten L, Bloemena E, Merkus P, Hensen EF.
    Schneiderian papilloma of the temporal bone.
    BMJ Case Rep. 2013 Dec 5;2013.
  • Rietbergen MM, Braakhuis BJ, Moukhtari N, Bloemena E, Brink A, Sie D, Ylstra B, Baatenburg de Jong RJ, Snijders PJ, Brakenhoff RH, Leemans CR.
    No evidence for active human papillomavirus (HPV) in fields surrounding HPV-positive oropharyngeal tumors.
    J Oral Pathol Med. 2014 Feb;43(2):137-42.
  • Braakhuis B, Rietbergen M, Buijze M, Snijders P, Bloemena E, Brakenhoff R, Leemans C.
    TP53 mutation and human papilloma virus status of oral squamous cell carcinomas in young adult patients.
    Oral Dis. 2013 Aug 23.
  • Rietbergen MM, Brakenhoff RH, Bloemena E, Witte BI, Snijders PJ, Heideman DA, Boon D, Koljenovic S, Baatenburg-de Jong RJ, Leemans CR.
    Human papillomavirus detection and comorbidity: critical issues in selection of patients with oropharyngeal cancer for treatment De-escalation trials.
    Ann Oncol. 2013 Nov;24(11):2740-5.
  • van Weert S, Bloemena E, van der Waal I, de Bree R, Rietveld DH, Kuik JD, Leemans CR.
    Adenoid cystic carcinoma of the head and neck: a single-center analysis of 105 consecutive cases over a 30-year period.
    Oral Oncol. 2013 Aug;49(8):824-9.
  • Ho AS, Kannan K, Roy DM, Morris LG, Ganly I, Katabi N, Ramaswami D, Walsh LA, Eng S, Huse JT, Zhang J, Dolgalev I, Huberman K, Heguy A, Viale A, Drobnjak M, Leversha MA, Rice CE, Singh B, Iyer NG, Leemans CR, Bloemena E, Ferris RL, Seethala RR, Gross BE, Liang Y, Sinha R, Peng L, Raphael BJ, Turcan S, Gong Y, Schultz N, Kim S, Chiosea S, Shah JP, Sander C, Lee W, Chan TA.
    The mutational landscape of adenoid cystic carcinoma.
    Nat Genet. 2013 Jul;45(7):791-8.
  • Lo Galbo AM, Kuik DJ, Lips P, von Blomberg BM, Bloemena E, Leemans CR, Debree R.
    A prospective longitudinal study on endocrine dysfunction following treatment of laryngeal or hypopharyngeal carcinoma.
    Oral Oncol. 2013 Sep;49(9):950-5.
  • Matse JH, Yoshizawa J, Wang X, Elashoff D, Bolscher JG, Veerman EC, Bloemena E, Wong DT.
    Discovery and prevalidation of salivary extracellular microRNA biomarkers panel for the noninvasive detection of benign and malignant parotid gland tumors.
    Clin Cancer Res. 2013 Jun 1;19(11):3032-8.
  • van Boerdonk RA, Daniels JM, Bloemena E, Krijgsman O, Steenbergen RD, Brakenhoff RH, Grünberg K, Ylstra B, Meijer CJ, Smit EF, Snijders PJ, Heideman DA.
    J Thorac Oncol. 2013 Jun;8(6):711-8.
  • Brouns E, Baart J, Karagozoglu Kh, Aartman I, Bloemena E, van der Waal I.
    Malignant transformation of oral leukoplakia in a well-defined cohort of 144 patients.
    Oral Dis. 2014 Apr;20(3):e19-24.
  • Rietbergen MM, Leemans CR, Bloemena E, Heideman DA, Braakhuis BJ, Hesselink AT, Witte BI, Baatenburg de Jong RJ, Meijer CJ, Snijders PJ, Brakenhoff RH.
    Increasing prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as assessed by a validated test algorithm.
    Int J Cancer. 2013 Apr 1;132(7):1565-71.
  • Flach GB, Tenhagen M, de Bree R, Brakenhoff RH, van der Waal I, Bloemena E, Kuik DJ, Castelijns JA, Leemans CR.
    Outcome of patients with early stage oral cancer managed by an observation strategy towards the N0 neck using ultrasound guided fine needle aspiration cytology: No survival difference as compared to elective neck dissection.
    Oral Oncol. 2013 Feb;49(2):157-64.
  • Flach GB, Bloemena E, van Schie A, Hoekstra OS, van Weert S, Leemans CR, de Bree R.
    Sentinel node identification in laryngeal cancer: Feasible in primary cancer with previously untreated neck.
    Oral Oncol. 2013 Feb;49(2):165-8.
  • Brouns E, Baart J, Karagozoglu K, Aartman I, Bloemena E, van der Waal I.
    Treatment results of CO(2) laser vaporisation in a cohort of 35 patients with oral leukoplakia.
    Oral Dis. 2012 [Epub ahead of print] PubMed PMID: 23323859.
  • Turksma AW, Braakhuis BJ, Bloemena E, Meijer CJ, Leemans CR, Hooijberg E.
    Immunotherapy for head and neck cancer patients: shifting the balance.
    Immunotherapy. 2013 Jan;5(1):49-61.
  • Brouns ER, Baart JA, Bloemena E, Karagozoglu H, van der Waal I.
    The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients.
    Med Oral Patol Oral Cir Bucal. 2013 Jan 1;18(1):e19-26.
  • Turksma A, Bontkes H, van den Heuvel H, de Gruijl T, von Blomberg B, Braakhuis B, Leemans C, Bloemena E, Meijer C, Hooijberg E.
    Effector memory T-cell frequencies in relation to tumour stage, location and HPV status in HNSCC patients.
    Oral Dis. 2012 Oct 24.[Epub ahead of print]
  • Graveland AP, Braakhuis BJ, Eerenstein SE, de Bree R, Bloemena E, de Maaker M, van den Brekel MW, Dijk F, Mesker WE, Tanke HJ, Leemans CR, Brakenhoff RH.
    Molecular diagnosis of minimal residual disease in head and neck cancer patients.
    Cell Oncol (Dordr). 2012 Oct;35(5):367-75.
  • Heuveling DA, Flach GB, van Schie A, van Weert S, Karagozoglu KH, Bloemena E, Leemans CR, de Bree R.
    Visualization of the sentinel node in early-stage oral cancer: limited value of late static lymphoscintigraphy.
    Nucl Med Commun. 2012 Oct;33(10):1065-9.
  • Wijs RW, Meleti M, Bloemena E, van der Waal I.
    [A non-pigmented naevus as an uncommon gingival swelling].
    Ned Tijdschr Tandheelkd. 2012 Jun;119(6):283-4. Dutch.
  • van Zeeburg HJ, Graveland AP, Brink A, Nguyen M, Leemans CR, Bloemena E, Braakhuis BJ, Brakenhoff RH.
    Generation of precursor cell lines from preneoplastic fields surrounding head and neck cancers.
    Head Neck. 2012 Jun 19.
  • Brouns ER, Bloemena E, Belien JA, Broeckaert MA, Aartman IH, van der Waal I.
    DNA ploidy measurement in oral leukoplakia: different results between flow and image cytometry.
    Oral Oncol. 2012 Jul;48(7):636-40.
  • Gurney BA, Schilling C, Putcha V, Alkureishi LW, Alvarez AJ, Bakholdt V, Barbier Herrero L, Barzan L, Bilde A, Bloemena E, Salces CC, Dalla Palma P, de Bree R, Dequanter D, Dolivet G, Donner D, Flach GB, Fresno M, Grandi C, Haerle S, Huber GF, Hunter K, Lawson G, Leroux A, Lothaire PH, Mamelle G, Silini EM, Mastronicola R, Odell EW, O'Doherty MJ, Poli T, Rahimi S, Ross GL, Zuazua JS, Santini S, Sebbesen L, Shoaib T, Sloan P, Sorensen JA, Soutar DS, Therkildsen MH, Vigili MG, Villarreal PM, von Buchwald C, Werner JA, Wiegand S, McGurk M.
    Implications of a positive sentinel node in oral squamous cell carcinoma.
    Head Neck. 2012 Nov;34(11):1580-5.
  • Hertog D, Bloemena E, Aartman IH, van-der-Waal I.
    Histopathology of ameloblastoma of the jaws; some critical observations based on a 40 years single institution experience.
    Med Oral Patol Oral Cir Bucal. 2012 Jan 1;17(1):e76-82.
  • de Weger VA, Turksma AW, Voorham QJ, Euler Z, Bril H, van den Eertwegh AJ, Bloemena E, Pinedo HM, Vermorken JB, van Tinteren H, Meijer GA, Hooijberg E.
    Clinical effects of adjuvant active specific immunotherapy differ between patients with microsatellite-stable and microsatellite-instable colon cancer.
    Clin Cancer Res. 2012 Feb 1;18(3):882-9.
  • van den Brekel MW, Lodder WL, Stel HV, Bloemena E, Leemans CR, van der Waal I.
    Observer variation in the histopathologic assessment of extranodal tumor spread in lymph node metastases in the neck.
    Head Neck. 2012 Jun;34(6):840-5.
  • Flach GB, Broglie MA, van Schie A, Bloemena E, Leemans CR, de Bree R, Stoeckli SJ.
    Sentinel node biopsy for oral and oropharyngeal squamous cell carcinoma in the previously treated neck.
    Oral Oncol. 2012 Jan;48(1):85-9.
  • Bremmer JF, Brakenhoff RH, Broeckaert MA, Beliën JA, Leemans CR, Bloemena E, van der Waal I, Braakhuis BJ.
    Prognostic value of DNA ploidy status in patients with oral leukoplakia.
    Oral Oncol. 2011 Oct;47(10):956-60.
  • Karagozoglu KH, Castelijns J, Bloemena E, de Bree R, van der Waal I.
    [An enlarged lymph node in the neck; what to do?].
    Ned Tijdschr Tandheelkd. 2011; 118:267-71. Dutch.
  • Van Geenen EJ, Smits MM, Schreuder TC, van der Peet DL, Bloemena E, Mulder CJ.
    smoking is related to pancreatic fibrosis in humans.
    Am J Gastroenterol.2011;106:1161-6.
  • Costa AF, Altemani A, Vékony H, Bloemena E, Fresno F, Suárez C, Llorente JL, Hermsen M.
    Genetic profile of adenoid cystic carcinomas (ACC) with high-grade transformation versus solid type.
    Cell Oncol (Dordr). 2011 May 4. [Epub ahead of print]
  • Lindenbergh-van der Plas M, Brakenhoff RH, Kuik DJ, Buijze M, Bloemena E, Snijders PJ, Leemans CR, Braakhuis BJ.
    Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma.
    Clin Cancer Res. 2011;17:3733-41.
  • Costa AF, Altemani A, Vékony H, Bloemena E, Fresno F, Suárez C, Llorente JL, Hermsen M.
    Genetic profile of adenoid cystic carcinomas (ACC) with high-grade transformation versus solid type.
    Anal Cell Pathol (Amst). 2010;33:217-28.
  • Van Geenen EJ, Smits MM, Schreuder TC, van der Peet DL, Bloemena E, Mulder CJ.
    Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease.
    Pancreas. 2010;39:1185-90.
  • Graveland AP, Golusinski PJ, Buijze M, Douma R, Sons N, Kuik DJ, Bloemena E, Leemans CR, Brakenhoff RH, Braakhuis BJ.
    Loss of heterozygosity at 9p and p53 immunopositivity in surgical margins predict local relapse in head and neck squamous cell carcinoma.
    Int J Cancer. 2010 2011;128:1852-9.
  • Flach GB, de Bree R, van Schie A, Hoekstra OS, Bloemena E, Castelijns JA, van der Waal I, Leemans CR
    [Sentinel node procedure in oral carcinoma. First experience with this method].
    Ned Tijdschr Geneeskd. 2010;154:A1254. Dutch.
  • Braakhuis BJ, Bloemena E, Leemans CR, Brakenhoff RH.
    Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue.
    Oral Oncol. 2010;46:485-91.
  • Vékony H, Röser K, Löning T, Ylstra B, van Wieringen W, van de Wiel M, Kok K, Leemans CR, van der Waal I, Bloemena E.
    Copy number gain at 8q12.1-q22.1 is associated with a malignant tumor phenotype in salvivary gland myoepitheliomas.
    Genes, Chromosomes and Cancer. 2009;48:202-212.
  • Vékony H, Leemans CR, Ylstra B, Meijer GA, Van der Waal I, Bloemena E.
    Salivary gland carcinoma: Oligonucleotide array CGH reveals similar genomic profiles in epithelial and mesenchymal components.
    Oral Oncology. 2009:45:259-265.
  • Schaaij-Visser TB, Graveland AP, Gauci S, Braakhuis BJ, Buijze M, Heck AJ, Kuik DJ ,
    Bloemena E, Leemans CR, Slijper M, Brakenhoff RH.
    Differential proteomics identifies protein biomarkers that predict local relapse of head and neck squamous cell carcinomas.
    Clin Cancer Res. 2009;15:7666-75.
  • Bremmer JF, Graveland AP, Brink A, Braakhuis BJ, Kuik DJ, Leemans CR, Bloemena E, Van der Waal I, Brakenhoff RH.
    Screening for oral precancer with noninvasive genetic cytology.
    Cancer Prev Res (Phila Pa). 2009;2:128-133.
  • Graveland AP, de Maaker M, Braakhuis BJ, de Bree R, Eerenstein SE, Bloemena E, Leemans CR, Brakenhoff RH.
    Moleculair detection of minimal residual cancer in surgical margins of head and neck cancer patients.
    Cell Oncol. 2009; 31:317-328.
  • Verwer BJ, Bouma G, Bloemena E, Schreuder TC, Mulder CJ, Van Nieuwkerk KM.
    Diagnosis and treatment of autoimmune hepatitis.
    Ned Tijdschr Geneeskd. 2009; 153:A247.
  • Verheij J, Voortman J, van Nieuwkerk CM, Jarbandhan SV, Mulder CJ, Bloemena E.
    Hepatic morphopathologic findings of lead poisoning in a drug addict: a case report.
    J Gastrointestin Liver Dis. 2009; 18:225-227.
  • De leest HT, Steen KS, Bloemena E, Lems WF, Kuipers EJ, van de Laar MA, Bijlsma JW,
    Janssen M, Houben HH, Kostense PJ, Boers M, Dijkmans BA.
    Helicobacter pylori eradication in patients on long-term treatment with NSAIDs reduces the severity of gastritis: a randomized controlled trial.
    J Clin Gastroenterol. 2009; 43:140-146.
  • Veenhoff AA, Bloemena E, Engel AF, van der Peet DL, Meijer OW, Cuesta MA.
    The relationship of histological tumor regression grade (TRG) and two different time intervals to surgery following radiation therapy for locally advanced rectal cancer.
    Int. J Colorectal Dis. 2009; 24:1091-1096.
  • Richir MC, van Lambalgen AA, Teerlink T, Wisselink W, Bloemena E, Prins HA, de Vries TP, van Leeuwen PA.
    Low arginine/asymmetric dimethylarginine ratio deteriorates systemic hemodynamics and organ blood flow in a rat model.
    Crit Care Med. 2009; 37:2010-2017.
  • Van Zeeburg HTJ, Snijders PJF, Wu T, Gluckman E, Soulier J, Surralles J, Castella M, van der Wal JE, Wennenberg J, Califano J, Velleuer E, Dietrich R, Ebell W, Bloemena E, Joentje H, Leemans CR, Brakenhoff RH.
    Clinical and molecular charcteristics of squamous cell carcinomas from Fanconi anemia patients.
    J Natl Cancer Inst. 2008; 100:1649-1653.
  • BremmerJF, Braakhuis BJ, Brink A, Broeckaert MA, Beliën JA, Meijer GA, Kuik DJ, René Leemans C, Bloemena E, van der Waal I, Brakenhoff RH.
    Comparative evaluation of genetic assays to identify oral pre-cancerous fields.
    J Oral Pathol. Med. 2008; 37:599-606.
  • Vékony H, Röser K, Löning T, Raaphorst FM, Leemans CR, Van der Waal I, Bloemena E.
    Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands.
    Histopathology, 2008; 53:658-666.
  • Bloemena E.
    Cancer and oncogenesis.
    Ned Tijdschr Tandheelkd. 2008; 115:180-185. Review.
  • Hadithi M, Cazemier M, Meijer GA, Bloemena E, Felt-Bersma RJ, Mulder CJ, Meuwissen SG, Pena AS, Van Bodegraven AA.
    Retrospective analysis of old-age colitis in the Dutch inflammatory bowel disease population.
    World J Gastroenterol. 2008; 14:3183-3187.
  • De Boer NK, Tuynman H, Bloemena E, Westerga J, Van der Peet DL, Mulder CJ, Cuesta MA, Meuwissen SG, Van Nieuwkerk CM, Van Bodegraven AA.
    Histopathology of liver biopsies from a thiopurine-naïve inflammatory bowel disease cohort: prevalence of nodular regenerative hyperplasia.
    Scand J Gastroenterol. 2008; 43:604-608.
  • Vékony H, Raaphorst FM, Otte AP, van Lohuizen M, Leemans CR, Van der Waal I, Bloemena E.
    High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma.
    J Clin Pathol. 2008; 6:744-749.
  • De Boer NK, Zondervan PE, Gilissen LP, Den Hartog G, Westerveld BD, Derijks LJ, Bloemena E, Engels LG, van Bodegraven AA, Mulder CJ.
    Absence of nodular regenerative hyperplasia after low-dose 6-thioguanine maintenance therapy in inflammatory bowel disease patients.
    Dig Liver Dis. 2008; 40:108-113.
  • Dekker JJ, Hage JJ, Karim RB, Bloemena E.
    Do histologic changes in the skin-lined neovagina of male-to-female transsexuals really occur?
    Ann Plast Surg. 2007; 59:546-549.
  • Hadithi M, Von Blomberg BM, Crusius JB, Bloemena E, Kostense PJ, Meijer JW, Mulder CJ, Stehouwer CD, Peña AS.
    Accuracy of serologic tests and HLA-DQ typing for diagnosing celiac disease.
    Ann Intern Med. 2007; 147: 294-302.
  • Vékony H, Ylstra B, Wilting SM, Meijer GA, van de Wiel MA, Leemans CR, van der Waal I, Bloemena E.
    DNA copy number gains at loci of growth factors and their receptors in salivary gland adenoid cystic carcinoma.
    Clin Cancer Res. 2007 ; 13:3133-1339.
  • Smid EJ, Stoter TR, Bloemena E, Lafleur MV, Leemans CR, Van der Waal I, Slotman BJ, Langendijk JA.
    The importance of immunohistochemical expression of EGFr in squamous cell carcinoma of the oral cavity treated with surgery and postoperative radiotherapy.
    Int J Radiat Oncol Biol Phys. 2006; 65:1323-1329.
  • Van Beek J, Zur Hausen A, Snel SN, Berkhof J, Kranenbarg EK, Van de Velde CJ, Van den Brule AJ, Middeldorp JM, Meijer CJLM, Bloemena E.
    Morphological evidence of an activated cytotoxic T-cell infiltrate in EBV-positive gastric carcinoma preventing lymph node metastases.
    Am J Surg Pathol. 2006; 30:59-65.
  • Haanen JB, Baars A, Gomez R, Weder P, Smits M, De Gruijl TD, Von Blomberg BM, Bloemena E, Scheper RJ, Van Ham SM, Pinedo HM, Van den Eertwegh AJ.
    Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients.
    Cancer Immunol Immunother. 2006; 55:451-458.
  • Bremmer JF, Braakhuis BJ, Ruijter-Schippers HJ, Brink A, Duarte HM, Kuik DJ, Bloemena E, Leemans CR, van der Waal I, Brakenhoff RH.
    A noninvasive genetic screening test to detect oral preneoplastic lesions.
    Lab Invest. 2005; 85:1481-1488.
  • Bloemena E.
    Pre-chewed.
    Ned Tijdschr Tandheelkd. 2004;111:316.
  • Heideman DA, Van Beusechem VW, Bloemena E, Snijders PJ, Craanen ME, Offerhaus GJ, Derksen PWB, De Bruin M, Witlox MA, Molenaar B, Meijer, CJLM, Gerritsen WR.
    Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.
    J Gene Med 2004; 6:317-327.
  • Van Beek J, Zur Hausen A, Klein Kranenbarg E, Van de Velde CJ, Middeldorp JM, Van den Brule AJ, Meijer CJLM, Bloemena E.
    EBV-positive gastric adenocarcinomas: a distinct clinicopathologic entity with a low frequency of lymph node involvement.
    J Clin Oncol 2004; 22:664-670.
  • Van Grieken NC, Meijer GA, Kale I, Bloemena E, Lindeman J, Offerhaus GJ , Meuwissen SGM, Baak JP, Kuipers EJ.
    Quantitative assessment of gastric antrum atrophy shows restitution to normal histology after Helicobacter pylori eradication.
    Digestion 2004; 69:27-33.
  • Zur Hausen A, Van Rees BP, Van Beek J, Craanen ME, Bloemena E, Offerhaus GJ, Meijer CJLM, Van den Brule AJC.
    Epstein-Barr virus in gastric carcinomas and gastric stump carcinomas: a late event in gastric carcinogenesis.
    J Clin Pathol 2004; 57:487-491.
  • Kroep JR, Van Groeningen CJ, Cuesta MA, Craanen ME, Hoekstra OS, Comans EF,
    Bloemena E, Hoekstra CJ, Golding RP, Twisk JWR, Peters GJ, Pinedo HM, Lammertsma AA.
    Positron emission tomography using 2-deoxy-2-[18F]-fluoro-D-glucose for response monitoring in locally advanced gastroesophageal cancer; a comparison of different analytical methods.
    Mol Imaging Biol 2003; 5:337-346.
  • Veerman EC, Van den Keijbus PA, Nazmi K, Vos W, Van der Wal JE, Bloemena E, Bolscher JGM, Nieuw Amerongen AV.
    Distinct localization of MUC5B glycoforms in the human salivary glands.
    Glycobiology 2003; 13:363-366.
  • Zur Hausen A, Van Beek J, Bloemena E, Ten Kate FJ, Meijer CJ, Van den Brule AJC.
    No role for Epstein-Barr virus in Dutch hepatocellular carcinoma: a study at the DNA, RNA and protein levels.
    J Gen Virol 2003; 84:1863-1869.
  • Backus HH, Van Groeningen CJ, Vos W, Dukers DF, Bloemena E, Wouters D, Pinedo HM, Peters GJ.
    Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases.
    J Clin Pathol 2002; 55:206-211.
  • Meij P, Leen A, Rickinson AB, Verkoeijen S, Vervoort MB, Bloemena E, Middeldorp JM.
    Identification and prevalence of CD8(+) T-cell responses directed against Epstein-Barr virus-encoded latent membrane protein 1 and latent membrane protein 2.
    Int J Cancer 2002; 99:93-99.
  • Meij P, Vervoort MB, Bloemena E, Schouten TE, Schwartz C, Grufferman S, Ambinder RF, Middeldorp JM.
    Antibody responses to Epstein-Barr virus-encoded latent membrane protein-1 (LMP1) and expression of LMP1 in juvenile Hodgkin's disease.
    J Med Virol 2002; 68:370-377.
  • Oudejans JJ, Harijadi H, Kummer JA, Tan IB, Bloemena E, Middeldorp JM, Bladergroen B, Dukers DF, Vos W, Meijer CJLM.
    High numbers of granzyme B/CD8-positive tumour-infiltrating lymphocytes in nasopharyngeal carcinoma biopsies predict rapid fatal outcome in patients treated with curative intent.
    J Pathol 2002; 198:468-475.
  • Peters GJ, Backus HH, Freemantle S, Van Triest B, Codacci-Pisanelli G, Van der Wilt CL, Smid K, Lunee J, Calvert AH, Marsh S, McLeod HL, Bloemena E, Meijer S, Jansen G, Van Groeningen CJ, Pinedo HM.
    Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism.
    Biochim Biophys Acta 2002; 1587:194-205.
  • Scholte GH, Van Doorn LJ, Cats A, Bloemena E, Lindeman J, Quint WG, Meuwissen SGM, Kuipers EJ.
    Genotyping of Helicobacter pylori in paraffin-embedded gastric biopsy specimens: relation to histological parameters and effects on therapy.
    Am J Gastroenterol 2002; 97:1687-1695.
  • Van Beek J, Zur Hausen A, Kranenbarg EK, Warring RJ, Bloemena E, Craanen ME, Van de Velde CJH, Middeldorp JM, Meijer CJLM, Van den Brule AJC.
    A rapid and reliable enzyme immunoassay PCR-based screening method to identify EBV-carrying gastric carcinomas.
    Mod Pathol 2002; 15:870-877.
  • Vermeer MH, Dukers DF, Ten Berge RL, Bloemena E, Wu L, Vos W, De Vries E, Tensen CP, Meijer CJLM, Willemze R.
    Differential expression of thymus and activation regulated chemokine and its receptor CCR4 in nodal and cutaneous anaplastic large-cell lymphomas and Hodgkin's disease.
    Mod Pathol 2002; 15(8):838-844.
  • Backus HH, Van Riel JM, Van Groeningen CJ, Vos W, Dukers DF, Bloemena E, Wouters D,Pinedo HM, Peters GJ.
    Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer.
    Ann Oncol 2001; 12(6):779-785.
  • Backus HH, Dukers DF, Van Groeningen CJ, Vos W, Bloemena E, Wouters D, Van Riel JM, Smid K, Giaccone G, Pinedo HM, Peters GJ.
    5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
    Ann Oncol 2001; 12:209-216.
  • Heideman DA, Snijders PJ, Craanen ME, Bloemena E, Meijer CJLM, Meuwissen SGM, Van Beusechem VW, Pinedo HM, Curiel DT, Haisma, HJ, Gerritsen WR.
    Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors.
    Cancer Gene Ther 2001; 8:342-351.
  • Heideman DA, Snijders PJ, Bloemena E, Meijer CJLM, Offerhaus GJ, Meuwissen SGM, Gerritsen WR, Craanen ME.
    Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.
    J Pathol 2001; 194:428-435.
  • Leen A, Meij P, Redchenko I, Middeldorp J, Bloemena E, Rickinson A, Blake N.
    Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses.
    J Virol 2001; 75:8649-8659.
  • Meij P, Bloemena E, Palmen N, Brink A, Vervoort MB, Meijer CJLM, Middeldorp JM.
    Functional CD4(+) and CD8(+) T-cell responses induced by autologous mitomycin C treated Epstein-Barr virus transformed lymphoblastoid cell lines.
    Cell Immunol 2001; 208:25-33.
  • Van Grieken NC, Weiss MM, Meijer GA, Bloemena E, Lindeman J, Offerhaus GJ, Meuwissen SGM, Baak JP, Kuipers EJ.
    Rapid quantitative assessment of gastric corpus atrophy in tissue sections.
    J Clin Pathol 2001; 54:63-69.
  • Van Grieken NC, Meijer GA, Weiss MM, Bloemena E, Lindeman J, Baak JP, Meuwissen SGM, Kuipers EJ.
    Quantitative assessment of gastric corpus atrophy in subjects using omeprazole: a randomized follow-up study.
    Am J Gastroenterol 2001; 96:2882-2886.
  • Zur Hausen A, Van Grieken NC, Meijer GA, Hermsen MA, Bloemena E, Meuwissen SGM, Baak JPA, Meijer CJLM, Kuipers EJ, Van den Brule AJC.
    Distinct chromosomal aberrations in Epstein-Barr virus-carrying gastric carcinomas tested by comparative genomic hybridization.
    Gastroenterology 2001; 121:612-618.
  • Cats A, Schenk BE, Bloemena E, Roosedaal R, Lindeman J, Biemond I, Klinkenberg-Knol EC, Meuwissen SGM, Kuipers EJ.
    Parietal cell protrusions and fundic gland cysts during omeprazole maintenance treatment.
    Hum Pathol 2000; 31:684-690.
  • Cats A, Bloemena E.
    J E. Reply.
    Hum Pathol 2000; 31:1537.
  • Dukers DF, Oudejans JJ, Jaspars EH, Gras M, Vos W, Middeldorp JM, Meijer CJLM, Bloemena E.
    All infiltrating T-lymphocytes in Hodgkin's disease express immunohistochemically detectable T-cell receptor zeta-chains in situ.
    Histopathology 2000; 36:544-550.
  • Dukers DF, Meij P, Vervoort MB, Vos W, Scheper RJ, Meijer CJLM, Bloemena E, Middeldorp JM.
    Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.
    J Immunol 2000; 165:663-670.
  • Hage JJ, Dekker JJ, Karim RB, Verheijen RH, Bloemena E.
    Ovarian cancer in female-to-male transsexuals: report of two cases.
    Gynecol Oncol 2000; 76:413-415.
  • Kanhai RC, Hage JJ, Van Diest PJ, Bloemena E, Mulder JW.
    Short-term and long-term histologic effects of castration and estrogen treatment on breast tissue of 14 male-to-female transsexuals in comparison with two chemically castrated men.
    Am J Surg Pathol 2000; 24:74-80.
  • Meij P, Vervoort MB, De Gooijer K, Bloemena E, Meijer CJ, Middeldorp JM.
    Bioreactor-scale production and one-step purification of Epstein-Barr nuclear antigen 1 expressed in baculovirus-infected insect cells.
    Protein Expr Purif 2000; 20:324-333.
  • Meij P, Vervoort MB, Meijer CJ, Bloemena E, Middeldorp JM.
    Production monitoring and purification of EBV encoded latent membrane protein 1 expressed and secreted by recombinant baculovirus infected insect cells.
    J Virol Methods 2000; 90:193-204.
  • Schenk BE, Kuipers EJ, Nelis GF, Bloemena E, Thijs JC, Snel ,Luckers AEG, Klinkenberg-Knol EC, Festen HPM, Viergever PP, Lindeman J, Meuwissen SGM.
    Effect of Helicobacter pylori eradication on chronic gastritis during omeprazole therapy.
    Gut 2000; 46:615-621.
  • Van Grieken NC, Weiss MM, Meijer GA, Hermsen MA, Scholte GH, Lindeman J, Craanen ME, Bloemena E, Meuwissen SGM,Baak JPA, Kuipers EJ.
    Helicobacter pylori-related and -non-related gastric cancers do not differ with respect to chromosomal aberrations.
    J Pathol 2000; 192:301-306.
  • Kanhai RC, Hage JJ, Bloemena E, Van Diest PJ, Karim RB.
    Mammary fibroadenoma in a male-to-female transsexual.
    Histopathology 1999; 35:183-185.
  • Meij P, Vervoort MB, Aarbiou J, van Dissel P, Brink A, Bloemena E, Meijer CJLM, Middeldorp JM.
    Restricted low-level human antibody responses against Epstein-Barr virus (EBV)-encoded latent membrane protein 1 in a subgroup of patients with EBV-associated diseases.
    J Infect Dis 1999; 179:1108-1115.
  • Schenk BE, Kuipers EJ, Klinkenberg-Knol EC, Bloemena E, Sandell M, Nelis GF, Snel P, Festen HPM, Meuwissen SGM.
    Atrophic gastritis during long-term omeprazole therapy affects serum vitamin B12 levels.
    Aliment Pharmacol Ther 1999; 13:1343-1346.
  • Vermorken JB, Claessen AM, Van Tinteren H, Gall HE, Ezinga R, Meijer S, Scheper RJ, Meijere CJLM, Bloemena E, Ransom JH, Hanna MG, Pinedo HM.
    Active specific immunotherapy for stage II and stage III human colon cancer: a randomised trial.
    Lancet 1999; 353:345-350.
  • Dieleman LA, Palmen MJ, Akol H, Bloemena E, Pena AS, Meuwissen SGM, Van Rees EP.
    Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines.
    Clin Exp Immunol 1998; 114:385-391.
  • Maas SM, Hage JJ, Cuesta MA, Bloemena E.
    Total laparoscopic ultrasonic colon dissection: is the colonic anastomosis safe?
    Surg Laparosc Endosc 1998; 8:404-405.
  • Nieuw Amerongen AV, Bolscher JG, Bloemena E, eerman EC.
    Sulfomucins in the human body.
    Biol Chem 1998; 379:1-18.
  • Schenk BE, Kuipers EJ, Klinkenberg-Knol EC, Bloemena E, Nelis GF, Festen HP, Jansen EH, Biemond I, Lamers CBHW, Meuwissen SGM.
    Hypergastrinaemia during long-term omeprazole therapy: influences of vagal nerve function, gastric emptying and Helicobacter pylori infection.
    Aliment Pharmacol Ther 1998; 12:605-612.
  • Mulder WM, Bloemena E, Stukart MJ, Kummer JA, Wagstaff J, Scheper RJ.
    T cell receptor-zeta and granzyme B expression in mononuclear cell infiltrates in normal colon mucosa and colon carcinoma.
    Gut 1997; 40:113-119.
  • Mulder WM, Stern PL, Stukart MJ, de Windt E, Butzelaar RM, Meijer S, Ader H, Claessen AME, Vermorken JB, Meijer CJLM, Wagstaff J, Scheper RJ, Bloemena E.
    Low intercellular adhesion molecule 1 and high 5T4 expression on tumor cells correlate with reduced disease-free survival in colorectal carcinoma patients.
    Clin Cancer Res 1997; 3:1923-1930.
  • Van Straalen WR, Hage JJ, Bloemena E, Glastra A.
    [Plastic surgery as a last resort in lichen sclerosus].
    Ned Tijdschr Geneeskd 1997; 141:992-998
  • Veerman EC, Bolscher JG, Appelmelk BJ, Bloemena E, Van den Berg TK, Nieuw Amerongen AV.
    A monoclonal antibody directed against high M(r) salivary mucins recognizes the SO3-3Gal beta 1-3GlcNAc moiety of sulfo-Lewis(a): a histochemical survey of human and rat tissue.
    Glycobiology 1997; 7:37-43.
  • Appelmelk BJ, Simoons-Smit I, Negrini R, Moran AP, Aspinall GO, Forte JG, de Vries T, Quan H, Verboom T, Maaskant JJ, Ghiara P, Kuipers E, Bloemena E, Tadema T, Townsend RR, Tyagarayan K, Crothers JM, Monteiro MA, Savio A, De Graaff J.
    Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity.
    Infect Immun 1996; 64:2031-2040.
  • Hage JJ, Karim RB, Bloemena E.
    Labial masses following vaginoplasty in male transsexuals: the differential diagnosis.
    Plast Reconstr Surg 1996; 97:1226-1232.
  • Jaspars LH, Bonnet P, Bloemena E, Meijer CJLM.
    Extracellular matrix and beta 1 integrin expression in nodal and extranodal T-cell lymphomas.
    J Pathol 1996; 178:36-43.
  • Mulder WM, Stukart MJ, de Windt E, Wagstaff J, Scheper RJ, Bloemena E.
    Mucin-1-related T cell infiltration in colorectal carcinoma.
    Cancer Immunol Immunother 1996; 42:351-356.
  • Vegter F, Hage JJ, Bloemena E.
    [Pseudoxanthoma elasticum; etiology, diagnosis and therapy].
    Ned Tijdschr Geneeskd 1996; 140:300-303.
  • Hage JJ, Karim RB, Asscheman H, Bloemena E, Cuesta MA.
    Unfavorable long-term results of rectosigmoid neocolpopoiesis.
    Plast Reconstr Surg 1995; 95:842-848.
  • Jaspars LH, Bloemena E, Bonnet P, Van der Valk P, Meijer CJLM.
    Distribution of extracellular matrix components and their receptors in human lymphoid tissue and B-cell non-Hodgkin lymphomas.
    Histopathology 1995; 26:113-121
  • Kuipers EJ, Uyterlinde AM, Pena AS, Hazenberg HJ, Bloemena E, Lindeman J, Klinkenberg-Knol EC, Meuwissen SGM.
    Increase of Helicobacter pylori-associated corpus gastritis during acid suppressive therapy: implications for long-term safety.
    Am J Gastroenterol 1995; 90:1401-1406.
  • Mulder WM, Stukart MJ, Roos M, Van Lier RA, Wagstaff J, Scheper RJ, Bloemena E.
    Culture of tumour-infiltrating lymphocytes from melanoma and colon carcinoma: removal of tumour cells does not affect tumour-specificity.
    Cancer Immunol Immunother 1995; 41:293-301.
  • Van Straalen WR, Hage JJ, Bloemena E.
    The inframammary ligament: myth or reality?
    Ann Plast Surg 1995; 35:237-241.
  • Jaspars EH, Bloemena E, Bonnet P, Scheper RJ, Kaiserling E, Meijer CJLM.
    A new monoclonal antibody (3A5) that recognises a fixative resistant epitope on tissue macrophages and monocytes.
    J Clin Pathol 1994; 47:248-252.
  • Mulder WM, Koenen H, Van de Muysenberg AJ, Bloemena E, Wagstaff J, Scheper RJ.
    Reduced expression of distinct T-cell CD molecules by collagenase/DNase treatment.
    Cancer Immunol Immunother 1994; 38:253-258.
  • Bloemena E, Gall H, Ransom JH, Pomato N, Murray JH, Bos E, Scheper RJ, Meijer CJLM, Hanna MG, Vermorken JB.
    Delayed-type hypersensitivity reactions to tumor-associated antigens in colon carcinoma patients immunized with an autologous tumor cell/Bacillus Calmette-Guerin vaccine.
    Cancer Res 1993; 53:456-459.
  • Hanna MG, Jr., Ransom JH, Pomato N, Peters L, Bloemena E, Vermorken JB et al.
    Active specific immunotherapy of human colorectal carcinoma with an autologous tumor cell/bacillus Calmette-Guerin vaccine.
    Ann N Y Acad Sci 1993; 690:135-146.
  • Raasveld MH, Bloemena E, Wilmink JM, Surachno S, Schellekens PT, Ten Berge RJ.
    Interleukin-6 and neopterin in renal transplant recipients: a longitudinal study.
    Transpl Int 1993; 6:89-94.
  • Raasveld MH, Bloemena E, Wertheim-van Dillen P, Surachno J, Wilmink JM, Ten Berge IJ.
    Serum neopterin/creatinine values correlate with severity of symptoms caused by cytomegalovirus infection in renal transplant recipients.
    Transpl Int 1993; 6:42-44.
  • Claessen AM, Bloemena E, Bril H, Meijer CJ, Scheper RJ.
    Locoregional administration of etoposide, but not of interleukin 2, facilitates active specific immunization in guinea pigs with advanced carcinoma.
    Cancer Res 1992; 52:2440-2446.
  • Raasveld MH, Bloemena E, Surachno S, Ten Berge RJ.
    T gamma/delta lymphocytes in renal transplant recipients.
    Nephrol Dial Transplant 1992; 7:530-533.
  • Zemel D, Ten Berge RJ, Struijk DG, Bloemena E, Koomen GC, Krediet RT.
    Interleukin-6 in CAPD patients without peritonitis: relationship to the intrinsic permeability of the peritoneal membrane.
    Clin Nephrol 1992; 37:97-103.
  • Bloemena E, Koopmans RP, Weinreich S, Van Boxtel CJ, Schellekens PT.
    Pharmacodynamic modeling of lymphocytopenia and whole blood lymphocyte cultures in prednisolone-treated individuals.
    Clin Immunol Immunopathol 1990; 57:374-386.
  • Bloemena E, Ten Berge IJ, Surachno J, Wilmink JM.
    Kinetics of interleukin 6 during OKT3 treatment in renal allograft recipients.
    Transplantation 1990; 50:330-331.
  • Bloemena E, Weinreich S, Schellekens PT.
    The influence of prednisolone on the recirculation of peripheral blood lymphocytes in vivo.
    Clin Exp Immunol 1990; 80:460-466.
  • Bloemena E, Van Oers RH, Weinreich S, Stilma-Meinesz AP, Schellekens PT, Van Lier RA.
    The influence of cyclosporin A on the alternative pathways of human T cell activation in vitro.
    Eur J Immunol 1989; 19:943-946.
  • Bloemena E, Roos MT, Van Heijst JL, Vossen JM, Schellekens PT.
    Whole-blood lymphocyte cultures.
    J Immunol Methods 1989; 122:161-167.
  • Bloemena E, van Lier RA, Van Oers MH, Weinreich S, Stilma-Meinesz AP, Schellekens PT.
    The effects of prednisolone and cyclosporin A on monocyte-dependent and -independent human T-cell proliferation in vitro.
    Transplant Proc 1989; 21:861-865.
  • Van der Heyden AA, Bloemena E, Out TA, Wilmink JM, Schellekens PT, Van Oers MH.
    The influence of immunosuppressive treatment on immune responsiveness in vivo in kidney transplant recipients.
    Transplantation 1989; 48:44-47.
  • Van Lier R, Bloemena E, Brouwer M, Van Heijst J, Weinreich S, Aarden L.
    Studies on the monocyte dependence of T-cell proliferation induced by monoclonal antibodies directed against regions I and II of the CD2 antigen.
    Immunology 1989; 67:333-338.
  • Bloemena E, Van Oers MH, Weinreich S, Yong SL, Schellekens PT.
    Prednisolone and cyclosporin A exert differential inhibitory effects on T-cell proliferation in vitro.
    Clin Immunol Immunopathol 1988; 48:380-391.
  • Bloemena E, Van Oers MH, Weinreich S, Yong SL, Schellekens PT.
    Cyclosporine A does not prevent expression of biologically active IL 2 receptors in vitro.
    Transplant Proc 1988; 20:131-135.
  • Bloemena E, Van Oers MH, Weinreich S, Schellekens PT.
    Cyclosporin A and prednisolone do not inhibit the expression of high-affinity receptors for interleukin 2.
    Clin Exp Immunol 1988; 71:308-313.